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SELECTED PUBLICATIONS
C. I. Mateo, P. M. Knutsen, P. S.
Tsai, A. Y. Shih and D. Kleinfeld,
Entrainment of arteriole vasomotor fluctuations
by neuronal activity: A basis of blood oxygen
level dependent "resting state" connectivity
across cortex. Neuron (2017) 20(3):406-416
P. S. Tsai, C. Mateo, J.J. Field, C.B.
Schaffer, M.E. Anderson & D. Kleinfeld,
Ultra-large field-of-view two-photon microscopy.
Optics Express (2015) 23: 13833-13847
D. C. Jeong, P. S. Tsai and D.
Kleinfeld, All-optical osteotomy to create
windows for transcranial imaging in mice. Optics
Express 21:23160-23168 (2013).
P. Blinder*, P. S. Tsai*,
J. P. Kaufhold, P. M. Knutsen, H. Suhl and D.
Kleinfeld, The
cortical angiome: An interconnected vascular network with
noncolumnar patterns of blood flow. Nature Neuroscience 16:889-897
(2013).
A. Y. Shih, P. Blinder, P. S. Tsai,
B. Friedman, G. Stanley, P. D. Lyden and D.
Kleinfeld,The smallest stroke: Occlusion of one
penetrating vessel leads to infarction and a cognitive
deficit. Nature
Neuroscience 16:55-63 (2013).
J.
P. Kaufhold, P. S. Tsai, P.
Blinder and D. Kleinfeld, Vectorization
of optically sectioned brain microvasculature:
Learning aids completion of vascular graphs by
connecting gaps and
deleting open-ended segments,
Medical Image Analysis (2012).
P. J. Drew, A. Y. Shih, P.
Knutsen, D. Davalos, P. Blinder, K. Akassoglou,
P. S. Tsai
and D. Kleinfeld, Chronic
imaging and optical manipulation of cortical
cells and microvessels through a large-area
polished and reinforced thinned-skull.
Nature Methods.,981-984, (2010).
D. N. Vitek, D. E. Adams, A. Johnson, P.
S. Tsai, S. Backus, C. G.
Durfee, D. Kleinfeld and J. A. Squier, Temporally
focused femtosecond laser pulses for low
numerical aperture micromachining through
optically transparent materials.
Optics Express 18:18086-18094, (2010).
P. S. Tsai, J. Kaufhold, P.
Blinder, B. Friedman, P.J. Drew, H.J. Karten, P.
D. Lyden and D. Kleinfeld,
Correlations of neuronal and microvascular
densisties in murine cortex revealed by direct
counting and colocalization of nuclei and
vessels, Journal of
Neuroscience, 29(46)
14553-14570 (2009).
P. S. Tsai, B.
Migliori, K. Campbell, T. N. Kim, Z. Kam, A.
Groisman, and D. Kleinfeld, Spherical
aberration correction in nonlinear microscopy
and optical ablation using a transparent
deformable membrane, Applied
Physics Letters, 91(19),
191102 (2007).
N. Nishimura, C. B. Schaffer, B. Friedman, P. S. Tsai,
P. D. Lyden, and D. Kleinfeld, Targeted insult to individual subsurface cortical blood vessels
using ultrashort laser pulses: Three models of
stroke. Nature
Methods, 3, 99 (2006).
C. B. Schaffer, B. Friedman, N. Nishimura, L. F.
Schroeder, P. S. Tsai, F. F. Ebner, P. D. Lyden, and D.
Kleinfeld, Two-photon
imaging of cortical surface microvessels reveals
a robust redistribution in blood flow after
vascular occlusion,
Public Library of Science Biology, 4 (2), e22
(2006)
P. S. Tsai, B.
Friedman, A. I. Ifarraguerri, B. D. Thompson, V.
Lev-Ram, C. B. Schaffer, Q. Xiong, R. Y. Tsien, J.
A. Squier, and D. Kleinfeld, All-Optical Histology Using Ultrashort
Laser Pulses, Neuron,
39,
27 (2003).
P. S. Tsai, N. Nishimura, E. J.
Yoder, E. M. Dolnick, G. A. White, and D.
Kleinfeld, Principles, design,
and construction of a two photon laser
scanning microscope for in vitro and in
vivo brain imaging in In Vivo Optical
Imaging of Brain Function, R. D. Frostig,
ed.,Broca Raton, CRC Press, pp. p113-171
(2002).
J. A. Davis, P. S. Tsai, D.M. Cottrell, T. Sonehara, J. Amako, Transmission Variations in Liquid
Crystal Spatial Light Modulators Caused by
Interference and Diffraction Effects. Optical Engineering, 38, 1051
(1999).
J. A. Davis, I. Moreno, P.
S. Tsai, Polarization Eigenstates for
Twisted-Nematic Liquid-Crystal Displays, Applied Optics, 37, 937 (1998).
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